With reference to the scientific progress of ancient India, which of the statements given below are

correct?

• 1. Different kinds of specialized surgical instruments were in common use by 1st century AD.
• 2. Transplant of internal organs in the human body had begun by the beginning of 3rd century AD.
• 3. The concept of sine of an angle was known in 5th century AD.
• 4. The concept of cyclic quadrilaterals was known in 7th century AD.

Select the correct answer using the codes given below: